We were running SQL Compact and were at about 1200 assets and just moved everything to our MSSQL server. If you plan on being anywhere near 1000 assets (this includes desktops, laptops, switches, monitors, printers, etc), I would highly recommend going the full server route. We were seeing major slow downs of the interface when trying to move pages, search, etc which all went away after moving the database onto our SQL Server.
Honestly, if you already have a SQL Server running for other databases, I would just go ahead and put your Lansweeper DB on there. No reason not to.