This should get you started:
Select Top 1000000 tblAssets.AssetID,
tblAssets.AssetName
From tblAssets
Inner Join tblAssetCustom On tblAssetCustom.AssetID = tblAssets.AssetID
Where tblAssetCustom.State = 1 And tblAssets.Assettype = -1 And
Not Exists(Select tblQuickFixEngineering.AssetID
From tblQuickFixEngineering Inner Join tblQuickFixEngineeringUni
On tblQuickFixEngineeringUni.QFEID = tblQuickFixEngineering.QFEID
Where tblQuickFixEngineering.AssetID = tblAssets.AssetID And
tblQuickFixEngineeringUni.HotFixID = 'KB2921916')
Order By tblAssets.AssetName