Dear FrankSc,
Thank you for the reply.
So the ping will originate from the server hosting the Lansweeper Web page? That part should give correct replies for us.
However, since we are scanning devices that are in separate domains the NetBIOS will not always resolve for the devices in other domains, is there any general recommendations on setting up 'DNS Suffix Search List' or similar on the server hosting the Lansweeper web service to achieve functional cross domain pings?